UNPARALLELED
ANTI-AGEING PERFORMANCE.

CLINICALLY TESTED AGAINST RETINOL.

BACKED BY 5 INDEPENDENT CLINICAL TRIALS.

In a series of independent clinical trials conducted by the Korean Skin Centre, REGENEX^TM significantly outperformed Retinol in both wrinkle reduction and depigmentation.

[1] Clinical study on forehead wrinkles on 21 subjects by Dermapro Skin Research Center.

UNPARALLELED
ANTI-AGEING PERFORMANCE.

Studied thoroughly, this powerful, patent-pending technology combines some of the most cutting edge active ingredients to regenerate skin cells.

7.2X BETTER WRINKLE REDUCTION VS RETINOL.

Figure 1. Images of periorbital (around eyes) wrinkle following 8 weeks consecutive application of the REGENEX^TM Renewal Serum.

Figure 2. Changes in average overall wrinkle size following 8 consecutive weeks application of REGENEX^TM and Retinol.

Clinical Results - In 8 Weeks:

(1) Glabellar (Between Brows) Average Overall Wrinkle Size Reduction

REGENEX^TM : - 10.4%
Retinol: - 5.7%

(2) Nasolabial (Side of Nose to Mouth) Folds Average Overall Wrinkle Size Reduction

REGENEX^TM: - 8.9%
Retinol: - 3.6%

(3) Upper Lip Average Overall Wrinkle Size Reduction

REGENEX^TM : - 6.2%
Retinol: - 3.31%

(4) Periorbital (Around Eyes) Wrinkle Average Overall Wrinkle Size Reduction

REGENEX^TM: - 8.2%
Retinol: - 5.5%

(5) Forehead Wrinkle Average Overall Wrinkle Size Reduction

REGENEX^TM: - 9.5%
Retinol: - 1.2%

Key Observation:
In 4 weeks: 7.2x better anti-ageing results than Retinol for forehead wrinkles.

Study Overview:
Comparing the efficacies of Modern Molecules REGENEX^TM Renewal Serum and Retinol for reducing the appearance of wrinkles.

Subjects:
21 male and female subjects aged 49 to 60 years old with varying signs of facial ageing.

Methodology:
Randomised and placebo-controlled study with 1:1 ratio of participants applying on opposite sides of the face: on one half of the face Modern Molecules REGENEX^TM Renewal Serum against placebo base cream with Retinol on the other half. Applied daily over 8 weeks.
Assessments conducted at 0, 2, 4, 6, and 8 weeks at 5 wrinkles sites (glabellar, nasolabial folds, upper lip, periorbital, forehead) for overall size, depth, width and maximum depth via 3D imaging.

Test Centre:
Dermapro Skin Research Center 
Seoul, Republic of Korea 
June, 2024 - August, 2024

17X BETTER ANTI-PIGMENTATION VS RETINOL.

Figure 1. Images of skin colour in hyperpigmentation area following 8 weeks of application of REGENEX^TM Renewal Serum.

Figure 2. Changes in hyperpigmentation following 8 consecutive weeks application of REGENEX^TM and Retinol.

Clinical Results - In 8 Weeks:
Statistical analysis of skin colour in hyperpigmentation area parameter after 8 weeks

REGENEX^TM L*Value Reduction: - 1.61%
Retinol  L*Value Reduction: - 0.35%

*The L* value correlates with the level of pigmentation of the skin.

Key Observation:
In 2 weeks: 17x more reduction in hyperpigmentation than Retinol

Study Overview:
Comparing the efficacies of Modern Molecules REGENEX^TM Renewal Serum and Retinol for reducing the appearance of pigmentation and age spots.

Subjects:
21 male and female subjects aged 49 to 60 years old with hyper-pigmentation, age spots, or other uneven tone.

Methodology:
Randomised and placebo-controlled study with 1:1 ratio of participants applying on opposite sides of the face: on one half of the face Modern Molecules REGENEX^TM Renewal Serum against placebo base cream with Retinol on the other half. Applied daily over 8 weeks.
Assessments conducted at 0, 2, 4, 6, and 8 weeks on skin colour in hyperpigmentation measured using a Spectrophotometer.

Test Centre:
Dermapro Skin Research Center 
Seoul, Republic of Korea 
June, 2024 - August, 2024

89% PREFERS REGENEX^TM OVER RETINOL.

Figure 1. Images of subject #1’s skin comparing signs of ageing after 28 days of application of REGENEX^TM Renewal Serum.

Figure 2. Images of subject #2’s skin comparing signs of ageing after 28 days of application of REGENEX^TM Renewal Serum.

Qualitative Results - In 4 Weeks:

89% agree that REGENEX^TM is better than Retinol.
97% agree that skin looks firmer, lifted and plump.
93% agree that the skin looks more youthful.
97% agree that skin’s tone and texture improved.
73% saw reduction in skin pigmentation.
80% saw visible reduction in fine lines and wrinkles.
93% agree that skin looks and feels smoother.
90% agree that skin looks visibly brighter.

Study Overview:
User trial to gather consumer perception and capture visual performance of Modern Molecules REGENEX^TM Renewal Serum in reducing the appearance of all signs of ageing including wrinkles, pigmentation, roughness, uneven tone, dullness and lack of firmness in 4 weeks.

Subjects:
20 Female and 5 Male participants aged 30-52 years old with varying early sign of facial ageing.

Methodology:
Qualitative study with photos taken of skin at day 0 and week 4 alongside written feedback forms and testimonials to capture perceived formula benefits. Applied daily over 4 weeks.

Singapore, June 2024.

DELAYS AGEING BY 5.5 YEARS IN 2 MONTHS.

Figure 1. Images of skin comparing per-orbital wrinkles after 8 weeks of application of active ingredient.

Figure 2. Changes in skin tone and wrinkle size following 8 consecutive weeks application of Peptide Complex in REGENEX^TM.

Clinical Results - In 8 Weeks:

photo-induced ageing is delayed by 5½ years
- 39.4% surface occupied by deep wrinkles
- 16.2% skin roughness
+ 15.5% skin tone
- 32.9% wrinkle density
- 19.9% wrinkle depth
- 23.3% wrinkle volume

Study overview:
Examining the anti-ageing performance of the branded Peptide Complex active in REGENEX^TM for reducing the appearance of all signs of ageing including wrinkles, roughness and lack of elasticity and tone.

Subjects:
23 female participants with 56 years mean age and varying signs of facial ageing.

Methodology:
Twice daily application of a cream containing branded Peptide Complex active in REGENEX^TM for 2 months on one half of the face against placebo.
Assessments conducted before and after 2 months treatment across ageing parameters including wrinkle surface, density, depth, volume as well as skin roughness, elasticity and tone.

Test Centre:
Sederma, France
December 2012

+65% IN COLLAGEN PRODUCTION.

Figure 1. Changes in skin radiance and density following 2 consecutive weeks application of Exosomes in REGENEX^TM.

Clinical Results:
In-vitro (test tube) study:

65% increase in collagen production
71.7% increase in wound healing
83% increase in anti-inflammatory effect

In-vivo (23 female) in 2 weeks:

49.9% increase in skin radiance
47.2% increase in skin moisture
20.1% increase in skin density
5.1% increase in skin elasticity

Study overview:
Examining the anti-ageing performance of the branded Exosomes active in REGENEX^TM on skin cell regeneration key indicators such as collagen production, wound healing, skin radiance, moisture, density and elasticity.

Subjects:
In-vitro: Human dermal fibroblast cells.
In-vivo: 23 female participants aged 20-60 years old for 2 weeks.

Test Centre:
ABio Materials, Korea